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Its most distinctive physicochemical property is hydrolytic stability at low pH, unlike almost every peptide of comparable length, BPC-157 resists degradation in human gastric juice, a characteristic emphasised throughout the published work of Sikiric and colleagues (Curr Med Chem, 2012)

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Light stimulus activates melanopsin breakdown in retinal photoreceptive ganglion cells that, via the retinohypothalamic pathway, induce the inhibition of melatonin synthesis 12

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