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[13] Other drugs used for PD symptom management include amantadine (Symmetrel®), selegiline (Eldepryl®, deprenyl), dopamine agonists (bromocriptine, pergolide, pramipexole, ropinirole), and several anticholinergic drugs

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Targeting the key antioxidant Keap1/Nrf2 pathway, we found that genetic reduction of Keap1 or pharmacological inhibition by dimethyl fumarate significantly rescued the C9orf72 -related oxidative stress and motor deficits