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Data availability Structural coordinates were deposited in the PDB with accession codes PDB 9ED4 (mTORC1–RAG–Ragulator–4E-BP1), PDB 9ED6 (MLST8–RAG–Ragulator), PDB 9ED7 (fully active state of mTOR–RHEB) and PDB 9ED8 (intermediate state of mTOR–RHEB)

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Mechanism of action: what the research has investigated Published preclinical literature has explored several pathways through which BPC-157 may exert its observed effects