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The recommended starting point for finding UK trials is: NIHR Be Part of Research (bepartofresearch.nihr.ac.uk) — the UK's public-facing portal for finding and joining clinical research studies ClinicalTrials.gov and the EU Clinical Trials Register — international registries of ongoing studies, including the REDEFINE and TRIUMPH programmes Referral via a GP or specialist to a trial centre In the meantime, men with obesity or type 2 diabetes should be aware that NICE-approved treatments are already available and may offer meaningful clinical benefit: Semaglutide (Wegovy®) is approved by NICE (TA875) for weight management in adults with a BMI ≥35 kg/m² (or lower thresholds for certain ethnic groups) and at least one weight-related comorbidity, subject to specialist tier service criteria and duration requirements