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In vitro studies in rats indicated that oral EE treatment resulted in reduced uterine Cyp1a1 mRNA expression, as well as intestinal Cyp1a1 , Nqo1 , and Gsta2 expression 23 whereas Hultman et al

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According to some authors, the interaction between dietary antioxidants and enzyme antioxidants forms an integrated antioxidant system that can help manage immune-mediated oxidative stress