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When a PBM contract transition happens (as with the CalPERS example above), a patient's previously preferred pharmacy can change without either the prescriber or patient initiating anything — worth a quick verification at the next visit for patients on maintenance medications, rather than assuming last year's pharmacy routing still applies

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The NMDAR channel is blocked by Mg 2+ at neuronal resting membrane potential, and Mg 2+ is removed when the membrane is depolarized (Jorratt et al., 2021