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According to a randomized, double-blind, placebo-controlled trial published in Arthritis & Rheumatism, researchers evaluated N-acetylcysteine (NAC) in patients with systemic lupus erythematosus (SLE). Participants received either placebo or NAC at doses of
Andersson A, Brattström L, Israelsson B, Isaksson A, Hamfelt A, and Hultberg B (1992)
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MiR-23a-3p, overexpressed among sorafenib non-responders, targets ACSL4 directly and leads to sorafenib resistance, while miR-23a-3p inhibition restores ACSL4 expression and triggers ferroptosis in hepatocellular carcinoma treated with sorafenib [133]