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Nevertheless, since omega-3 fatty acids and their metabolites might modulate pivotal molecular pathways including metabolic routes for the three amino acids (cysteine, glycine, and glutamate) needed for GSH biosynthesis, this feature could represent a promising field of knowledge to be explored

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In patients with severe ulcerative colitis who suffer frequent relapses, 5-ASA may not be sufficient, and more potent azathioprine and 6-MP will be necessary to maintain remissions