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It is distributed across various cellular compartments, with a notable presence in mitochondria (approximately 10-15%), the nucleus, and the endoplasmic reticulum [26]

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Grape seed proanthocyanidins ameliorate pancreatic beta‐cell dysfunction and death in low‐dose streptozotocin‐ and high‐carbohydrate/high‐fat diet‐induced diabetic rats partially by regulating endoplasmic reticulum stress