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Fat soluble vitamins, such as Vitamin D and Vitamin E, transfer into human milk easily and increase the levels of that vitamin available to the breastfed infant

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Secondly, therapeutic heterogeneity: clinical trials exhibit marked heterogeneity, such as the efficacy of probiotics or prebiotics being influenced by the baseline microbiota of host, diabetic duration, and glycemic control, while the scarcity of large-scale, multicenter RCT data hinders the establishment of uniform treatment standards