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BMPR2 crosstalk with other signaling pathways BMPR2 crosstalk with TGF-β/MAPK/PI3K/Akt The expression of BMPR2 is usually reduced in multiple PH groups, which participates in pulmonary vascular remodeling by inhibiting the BMPR2 signaling pathway while activating other signaling pathways especially TGF-β

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doi: 10.1001/archinternmed.2009.6

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