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Black Raspberry Extract Enhances Glutathione Conjugation of the Fjord-Region Diol Epoxide Derived from the Tobacco Carcinogen Dibenzo[def,p]chrysene in Human Oral Cells | Chemical Research in Toxicology

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Mechanistically, 5-ALA-PDT enhances the cytotoxic activity of CD8+ T cells by upregulating the expression of granzyme B and chemokine receptor 3 (CXCR3) while simultaneously downregulating programmed cell death protein 1 (PD-1) to prevent immune exhaustion (7)