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4AQ 4-aminoquinoline, 4AQR 4-aminoquinoline retinopathy, IL interleukin, IFN interferon, TNF tumor necrosis factor, DNA deoxyribonucleic acid, RNA ribonucleic acid, SLE systemic lupus erythematosus, RA rheumatoid arthritis, RPE retinal pigment epithelium, HIV human immunodeficiency virus, TLR toll-like receptor, HMG-CoA 3-hydroxy-3-methylglutaryl-coenzyme A reductase, mRNA mitochondrial ribonucleic acid, LDL low-density lipoprotein, SARS severe acute respiratory syndrome, APC antigen presenting cell Pharmacologic Tools for Dissecting the Mechanism of Action of 4-Aminoquinolines A recurring theme in papers written on the mechanism of action of chloroquine and hydroxychloroquine is the use of bafilomycin and ammonium acetate
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