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Curcuma xanthorrhiza Rhizome Extract Attenuates the Complete Freund's Adjuvant-induced Rheumatoid Arthritis in Rats - Patrick A. Kalona, Uma Sundaresan, Chellappandian M., Ariharasivakumar G., 2026

Most adverse effects (AEs) were grade 1/2

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T cell function in the TME is affected by lactate, lactic acid inhibits the effector functions of CD4 + and CD8 + T cells