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In a phase 3 study that compared ATRA plus ATO and ATRA plus Idarubicin, 27 % of patients (20 out of 74) in the ATRA plus IDA group remained MRD positive while 44 % (36 out of 82 maintained RT-qPCR positivity 60 days after induction.34 The adequate timepoint for assessing MRD using RT-PCR or RT-qPCR is at marrow recovery at the end of consolidation

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A nutrient-responsive hormonal circuit mediates an inter-tissue program regulating metabolic homeostasis in adult Drosophila

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