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Consistently, a recent study showed that DON exposure at the lower dose can trigger the activation of the inflammatory response in IPEC-J2 cells through the activation of the TNF-α/NF-κB/myosin light chain kinase (MLCK) pathway and it may be attributed to the inhibition of the aryl hydrocarbon receptor (AHR) pathway [117]

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Nonalcoholic steatohepatitis is the most rapidly growing indication for liver transplantation in patients with hepatocellular carcinoma in the U.S

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