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The study further revealed that under methionine deprivation, the long non-coding RNA PVT1 could interact with DNA Methyltransferase 3 (DNMT3) to modulate the DNA methylation level at the promoter region of the pro-apoptotic gene BNIP3

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Helicase-like transcription factor (HLTF)-deleted CDX/TME model of colorectal cancer increased transcription of oxidative phosphorylation genes and diverted glycolysis to boost S-glutathionylation in lymphatic intravascular metastatic niches