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[Abstract] Bone marrow cells cultured in medium containing 10 ng/mL GM-CSF for 3 days were treated with 2 μg PKH67-labeled sEVs with or without Amiloride (10 μM), Chlorpromazine (10 μM), or EIPA (5 μM) for 1 h

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Through this comprehensive large-scale MR analysis, we have, for the first time, established a causal and mediating relationship between gut microbiota, metabolites, and lung cancer, addressing the gaps left by prior research constrained by confounders and reverse causation