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IFN-γ at high concentrations is a cytokine that also increases intestinal permeability to large molecules ( Despite the increased LPS translocation into the blood described in numerous pathologies, it is not clear whether blood endotoxin levels are the result of LPS from the lumen or whether LPS is released by whole bacteria translocated in the lamina propria by the wall breakdown from effective host defense mechanisms and by autolysis (26)