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As an illustration, chitosan-coated liposomes carrying salmon calcitonin (sCT) peptide have been reported to increase mucoadhesion and epithelial uptake, with in vivo (rat) studies showing enhanced bioavailability and prolonged plasma exposure in addition to a consistent residence-time and protection with the mechanisms outlined above [48]

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The levels of nicotinamide adenine dinucleotide phosphate (reduced form) and nicotinamide adenine dinucleotide + (oxidized form) were assessed using the method proposed by Queval and Noctor (2007)