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cerana cerana, the expression of AccGSTS1 was high when exposed to various environmental stressors such as temperature (cold and heat shock), heavy metal (HgCl 2 ), pesticides (phoxim, cyhalothrin, and acaricide), H 2 O 2 , and ultraviolet 45 radiation which are known for their property to generate oxidative stress 55
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This dual impairment exacerbates excitation via weakened inhibitory neurotransmission, shifting the E/I balance toward hyperexcitability, manifesting as ASD-like behaviors, including social deficits and repetitive actions [120]