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Ginger and its ingredients regulate the Th-1, Th-2, Th-9, Th-17, Th-22, and Treg cell-related immune responses, down-regulating the B cell-related immune responses, modulate the macrophages-related responses, and the inflammatory mediator production and the adhesion molecules expression, interfere with the toll-like receptor (TLR)-related signaling pathways, suppress the inflammasomes and the oxidative stress (Jafarzadeh and Nemati, 2018)

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