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In rat models of PD, IN DFO has been reported to protect dopaminergic neurons in the substantia nigra and ameliorate motor deficits, suggesting IN DFO reaches the midbrain regions at pharmacologically active concentrations (Febbraro et al., 2013)

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While most cognitive enhancers work by temporarily boosting neurotransmitter function or providing acute stimulation, Dihexa actually promotes the formation of new synaptic connections—physically expanding the brain’s neural network capacity