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3.1.1 Nuclear receptor signaling disruption 3.1.1.1 Androgen receptor antagonism Bisphenol A exhibits androgenic antagonism, functioning as a competitive antagonist that blocks androgen receptor binding and subsequently reduces ARE-mediated gene transcription, with documented effects on androgen-dependent gene expression

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Cysteine is typically the rate-limiting substrate in GSH synthesis, which is why researchers studying glutathione supplementation have often focused on cysteine-delivery approaches alongside direct glutathione administration