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[71] reported that ferroptosis occurs in APAP-induced hepatic injury, showing that ferroptosis inhibitors such as ferrostatin-1 (Fer-1) provided moderate protection against APAP-induced death in primary mouse hepatocytes

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The in vivo TQ pharmacokinetic dose study showed a maximum concentration (Tmax) of 3.96±0.19 h reaching 4811.33±55.52 ng/ml as the maximum blood concentration (Cmax), while the elimination half-life (T1/2) was 4.4933±0.015 h