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The first approach was successfully applied in orthodox Western medicine, resulting in the discovery of morphine, salicin, papaverine, paclitaxel, etc., and their synthetic analogs and the current drug development platform, which is based mainly on the pharmacodynamics and pharmacokinetics of botanicals and accrues knowledge of interactions of biologically active molecules of plant extracts with receptor molecules, primarily proteins, involved in cellular and organism responses to achieve a therapeutic effect and maintain organismal homeostasis