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Section 5 of PL – How to store Photolabile medicines may require clear instructions e.g.: “Keep this medicine in its original packaging to protect it from light.” Protecting patient safety When photosensitivity risks are clearly identified and communicated, healthcare professionals can better counsel patients on preventive strategies – such as applying broad-spectrum sunscreens, avoiding sun exposure during peak hours, and using protective clothing

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Adagrasib and the KRYSTAL-1 trial Adagrasib is a covalent KRAS G12C inhibitor that traps the mutant protein in its inactive GDP-bound state