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Research endpoints include: β3-AR mRNA quantification in adipose tissue Lipoprotein lipase activity assays in adipose tissue homogenates Hormone-sensitive lipase phosphorylation profiling Free fatty acid mobilization measurements Indirect calorimetry for energy expenditure in metabolic chambers Fat mass quantification by DEXA or MRI Obesity Research Models The Ng 2000 obese Zucker rat study (Hormone Research, February 2000) established AOD 9604’s research framework for genetic obesity models

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Undoubtably, the field has many surprises to reveal in the coming years as we learn more about non-proteinaceous ubiquitylation, but such discoveries will require researchers to transition into areas not normally associated with ubiquitylation research and embrace technologies such as metabolomics, glycomics, and lipidomics