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For immunocompromised children ages 6 months through 4 years, eligibility for additional bivalent doses will depend on the vaccine previously received, the FDA said in a news release

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The β-lyase pathway may result in greater bioactivation of DCVC than does the oxidation pathway in rat proximal tubules, whereas the converse may be true for human proximal tubules (Cummings and Lash, 2000)