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Mechanistically, recent evidence suggests that circulating peptidoglycan fragments derived from gut bacteria may directly regulate microglial activation states (Spielbauer et al., 2024)

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Lambs 1mL at tailing or weaning Sheep 1.5 - 2.5mL pre-lambing Calves 5mL from 2 months of age Cows 10 - 12mL pre-calving Cobalt deficiency in soil and/or pasture leads to a lack of Vitamin B12 in body tissues of stock which, subsequently, may have poor growth rates and ill thrift, particularly in young animals Before treatment, establish pasture cobalt levels and/or Vitamin B12 status of stock Treatment is likely to last only 4-6 weeks if liver storage levels of Vitamin B12 and pasture levels of cobalt are low Treatment of pregnant ruminants should benefit newborn animals, particularly when treated in latter stages of pregnancy Supplementation of young ruminants should begin at or before weaning Seek veterinary advice if poor stock condition persists after treatment Milk and Meat NIL READ ENTIRE LABEL BEFORE USE May be harmful if swallowed FIRST AID If medical advice is needed, have a product container or label at hand