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The condition develops due to pathological interactions between skin immune cells and epidermal keratinocytes, leading to increased inflammation (due to the production of cytokines such as IL-17, IL-22, and TNF-α) and the excessive proliferation of keratinocytes, causing the characteristic alteration of skin called psoriatic plaque [7,57,105,110]
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To understand the role of delivery systems in more detail, read What Does a Glutathione Supplement Do