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explainable artificial intelligence (AI) frameworks offer a remedy but require harmonized input standards that remain elusive [210,219]

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2.5.3 Functio laesa: systemic organ damage SLE-associated systemic inflammation leads to damage in organs such as the heart, lungs, and liver, particularly in patients with hematological symptoms like leukopenia or thrombocytopenia due to the circulation and accumulation of auto-antibodies and inflammatory mediators throughout the body (330)