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Introduction (1→3)-β-D-Glucan (BDG) represents one of the most abundant components of the fungal and some bacterial cell walls and is a potent pathogen-associated molecular pattern (PAMP) in triggering the host response to infections ( Circulating monocytes serve as an integral part of the host response to infections by detecting PAMPs, phagocytosing/presenting antigens, and producing pro-inflammatory cytokines/chemokines to help recruit a larger wave of diverse leukocytes to the site of infection