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Enzymes that could be involved are: γ-glutamylcysteine synthetase, glutathione synthetase, glutathione peroxidase, glutathione disulfide reductase, glutathione-S-transferase, GSH or GSSG transport protein, cysteine or cystine transport proteins, glycine transport proteins, glutamate transport proteins, glucose-6-phosphate dehydrogenase, and many others

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The occurrence of leukemia may cause disorders in the metabolism of trace elements, resulting in an imbalance between the oxidative and antioxidant systems and accelerating the development of the disease