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doi: 10.3389/frdem.2026.1745504 Received 13 November 2025 Revised 21 December 2025 Accepted 16 January 2026 Published 04 February 2026 Volume 5 - 2026 Edited by Matea Nikolac Perković, Rudjer Boskovic Institute, Croatia Reviewed by Xifeng Wang, First Affiliated Hospital of Nanchang University, China Paolo Abondio, IRCCS Institute of Neurological Sciences of Bologna (ISNB), Italy Updates Copyright © 2026 Perezcano and Pérez-Coria
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MTHFR MTHFR is an enzyme in the methylation cycle that converts 5,10MTHF to 5-MTHF Methylene-tetrahydrofolate reductase, basically the conversion of inactive vitamin B9 to active vitamin B9