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However, in contrast to these findings, a more recent large-scale randomized trial found no differences in the number of chronic obstructive pulmonary disease exacerbations per year or the yearly rate of decline in the forced expiratory volume in one second when 600 mg of N -acetylcysteine was taken orally once daily (63)

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A previous report has indicated that licorice inhits the proliferation of H1975 non-small cell lung cancer (NSCLC) cells and MCF-7 breast cancer cells in a dose-dependent manner, potentially through the down-regulation of cyclin D1-CDK4 complex expression, and blocks tumor cells in G0/G1 phase