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Cognitive function and activities of daily living Although 40 Hz light stimulation demonstrated beneficial effects on brain structure, it did not yield significant improvements in cognitive function ( SMD = 0.16, 95% CI [-0.36 to 0.68], P = 0.55) or activities of daily living ( SMD = 0.53, 95% CI [-1.26, 2.33], P = 0.56), underscoring the necessity for future studies to explore the underlying mechanisms linking structural and functional changes