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In ARDS, an imbalance between these pathways contributes to exaggerated immune responses, tissue damage, and disease progression ( 2.1 Ferroptosis: a central player in ARDS pathogenesis Ferroptosis is a regulated, iron-dependent form of cell death distinguished by oxidative damage and lipid peroxidation

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Examples of in vivo models and veterinary clinical trials in antioxidant assays Fish models Zebrafish ( Danio rerio ) has emerged as a prominent model organism for in vivo antioxidant studies due to their transparent embryos, rapid development, genetic similarity to humans, and cost-effectiveness