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CAR-T cells against NKG2D ligand demonstrated potent senolytic ability across a variety of senescence stimuli such as irradiation, oncogenic mutation, and genotoxic etoposide

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Looking ahead, centralized multimodal repositories that integrate transcriptomic, proteomic and imaging data across neurological diseases will be essential to standardize reactive astrocyte definitions and foster cross-laboratory collaboration, ultimately refining subtype classification and accelerating translation