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When copper binds the peptide’s nitrogen donors, the surrounding atoms split the energy levels of copper’s d orbitals

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Descriptive histology and histomorphometry revealed that human platelet-derived growth factor-B gene delivery promotes the regeneration of both cementum and alveolar bone, while platelet-derived growth factor-1308, a dominant negative mutant of platelet-derived growth factor-A, has minimal effects on periodontal tissue regeneration