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Secretion of Thioredoxin In response to increased oxidative stress, Trx can be secreted by cells, although the precise mechanisms are not yet fully understood [75,76,77,78,79,80]

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In the dark, the plasma membranes of rod and cone photoreceptors in the outer segment are extremely permeable to cations, as evidenced by the so-called dark current, which is a continuous influx of sodium ions (Na + ) into the outer segments [52]