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The advanced oxidation protein products (AOPP), elevated in the plasma of patients with DKD, have been found to bind to the CD36 receptor, which can activate the Wnt/βcatenin signaling pathway as a result of lipid accumulation [48]

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A lack of RIP3 exacerbates liver injury in NASH, which may be related to a shift in hepatocytes from necrosis to apoptosis and an increase in the inflammatory response