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The search strategy employed a combination of the following keywords and MeSH terms: “Parkinson’s disease,” “ferroptosis,”“lipid peroxidation,” “alpha-synuclein,” “microglia,” “astrocytes,” “therapeutics,” and “neuroprotection.” The inclusion criteria focused on original research articles, reviews, and clinical trials published in English that elucidated molecular mechanisms, pathological features, or therapeutic strategies related to ferroptosis in PD

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One of these pathways, Rho Kinase, up regulates the production of SO within the artery wall