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232 Acetyl-L-carnitine is particularly important for nervous system function since it modulates neurotransmitter activity, increases activity of nerve growth factors, and appears to quiet pain signaling and inhibit pain sensitization

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The NIH/PMC systematic review on BPC-157 in orthopaedic sports medicine found that preclinical studies indicate its potential for promoting healing in musculoskeletal injuries including fractures, tendon ruptures and ligament tears, and noted that in one retrospective observation involving intraarticular injection for chronic knee pain, 7 of 12 patients reported relief for more than 6 months