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Frontiers | Oxidative Stress in Non-alcoholic Fatty Liver Disease. An Updated Mini Review

Consistent with the central role of glutamine in promoting CD4+ T cell differentiation into Th1 and Th17 cells (as described earlier in the amino acid section), glutamine starvation depletes intracellular αKG, reducing DNA methylation at the Foxp3 locus and thereby increasing Foxp3 expression, which skews differentiation toward Treg cells

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Although cysteine is not considered an essential amino acid, cysteine deficiency is associated with various diseases including metabolic disorders, immune dysfunction and cancer 1