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Polycyclic aromatic hydrocarbons, selected non-heterocyclic (EHC 202, 1998)

278 Notably, cerebrospinal fluid levels of SAM and the SAM/SAH ratio, as well as SAM levels in specific brain regions (cerebral cortical subdivisions, hippocampus, and putamen), are significantly decreased in patients with AD compared to controls, likely due to excessive utilization in polyamine biosynthesis

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elegans 1–11 (WormBook, 2006)