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As illustrated in Figure 3, these structural and biochemical alterations significantly shorten RBC lifespan, exacerbating anemia and contributing to the high cardiovascular risk observed in CKD patients

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10.1055/a-2069-4050 267 SilvestriniM.PasqualettiP.BaruffaldiR.BartoliniM.HandoukY.MatteisM.et al (2006)