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In the RAW 264.7 cell line, Que was also shown to counteract LPS-induced inflammation by phosphorylation of tyrosine phosphatidylinositol-3-kinase (PI3K)-p85 and complex formation of toll-like receptor 4 (TLR4)/MyD88/PI3K ( Oxidative stress occurs following an imbalance of the body’s antioxidant defence mechanisms and excessive generation of free radicals, and is involved in various pathologies such as diabetes, atherosclerosis, hypertension, neurodegenerative diseases, inflammation, and cancer (Oboh et al., 2016)

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Recently, DSePA was also studied for its radio-modulating activity in cancerous cells of lung origin (Table 2) [63]