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DT-109 treatment effectively reduced levels of several interleukins, including IL-2, IL-5, IL-7, IL-8, IL-12p70, IL-17A, and IL-21 (Figure 2F)

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It was shown that vitamin C can play a role in enhancing the antitumour effect of PLX4032 by significantly increasing mitigation of MAPK/ERK as well as PI3K/AKT pathway

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