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Addressing this, a shotgun proteomic approach on zone-specific hepatocytes isolated via immunostaining and subsequent FACS was used to explore the proteome map of the mouse liver lobule ( Overall, the ability to examine the spatial division of labor across the lobule had made significant strides in the last century (Figure 2)

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doi: 10.1016/j.lfs.2023.122145 42 BaHammamASPirzadaA